July 1, 2022

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In-Vitro ADME Services

In-Vitro ADME Services Market- Asia Pacific is presumed to witness the fastest growth

The in-vitro ADME services market size is expected to reach over US$ 5,238.9 million by 2028. The increasing research & development activities for drug development along with growing concern regarding animals for toxicity testing are the key factors for in-vitro ADME services market growth.

The in-vitro ADME services market report further mentioned that the market size raised at US$ 2,894.1 million in 2019, and it is likely to exhibit a Compound annual growth rate (CAGR) of 7.7% during the forecast period 2020 to 2028.

The increasing research & development activities

The increasing concern regarding animals for toxicity testing and increased research & development activities are the major factors for the growth of the global in-vitro ADME services market. As per recent statistics published in 2019, the overall amount spent on research & development activities in the pharmaceuticals/biotechnology industry has reached over US$ 165.0 billion from US$ 128.0 billion in 2008. ADME is the abbreviation for absorption, distribution, metabolism, and elimination, a pharmacology and pharmacokinetics term that describes the disposition of a drug or compound inside the human body.

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Rising demand from developing countries

The growing demand for in-vitro ADME services in emerging economies such as India, China, Brazil, and others due to rising drug discovery efforts in these countries is one of the key drivers anticipated to enhance the global in-vitro ADME services market growth over the forecast period. Furthermore, the ADME studies are considered essential for determining the efficacy and safety of drug candidates is another factor for the market demand.

Key Manufacturers Aim to Enhance Their Portfolios by Partnerships

According to Alchemy Research and Analytics major market players in the in-vitro ADME services market are focusing on strategies such as partnerships, collaboration, acquisitions, and mergers to enhance their geographic presence as well as product portfolio. The in-vitro ADME services market is highly fragmented.

A Significant Industry Development-

  • January 2020: Charles River Laboratories International Inc. announced that it had acquired HemaCare Corporation. HemaCare will become part of Charles River’s Research Models and Services segment. The acquisition of HemaCare Corporation expands Charles River’s scientific capabilities in the emerging, high-growth cell therapy sector, creating a comprehensive portfolio of early-stage research and manufacturing support solutions to help cell therapy developers and manufacturers advance their critical programs from basic research and proof-of-concept to regulatory approval and commercialization.

Market Trends

The increased contract research organizations (CROs) is one of the key trends observed by Alchemy Research and Analytics LLP in the years to come.  As per a recent article, nearly 95% of CROs have received operational approval and certification from the USFDA. In addition, companies have received necessary certifications from the EMA (50%), MHLW / PMDA (15%), ICH (13%), WHO (11%), MHRA (11%), followed by CFDA / MFDS / SFDA (9%) and TGA (4%).

Market Drivers

The major factors which are driving the growth of the in-vitro ADME services market are growing investment in research & development activities by pharmaceutical companies. As per recent statistics published in 2019, the overall research & development activities in the pharmaceutical industry have reached over US$ 165.0 billion in 2018.

Market Challenges

The in-vitro ADME services market challenges are the rising government regulations for research & development of the pharmaceutical industry. Alchemy Research and Analytics observed that the rising government regulations is the key restraint for the growth of the in-vitro ADME services market.

Segment Insights

Based on the type, the in-vitro ADME services market is categorized into solution properties, drug absorption and transport, drug metabolism, and drug-drug interaction. The drug absorption and transport category accounted for the largest share in the global in-vitro ADME services market in 2019 and had over 30% of the market revenue share in the same year. This is ascribed to the growing demand for novel technologies along with rising research & development activities in the biopharmaceutical and pharmaceutical industry. Drug absorption and transport mostly involve processes including parallel artificial membrane permeability assay (PAMPA) permeability screening, Caco-2 permeability screening, MDCK permeability, and transporter assay platform. Drug absorption and transport is followed by drug metabolism mainly owing to the presence of high market demand, increasing surveillance of regulatory bodies, and rising research and development activities in the field of medicine.

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